著者プロフィール
原 正彦（はら まさひこ）
1981年 兵庫県宝塚市生まれ
1996年 兵庫県立宝塚西高等学校
2005年 島根大学医学部医学科卒業／神戸赤十字病院（初期研修）
2007年 大阪労災病院（後期研修）
2010年 大阪大学医学部付属病院 循環器内科
2011年 大阪大学大学院医学系研究科 循環器内科学（大学院生）
2015年 大阪大学医学部附属病院 未来医療開発部（特任研究員）
2016年 一般社団法人日本臨床研究学会 代表理事／株式会社 mediVR 代表取締役／株式会社iDevice 代表取締役
2019年 国立大学法人 島根大学 地域包括ケア教育研究センター（客員教授）
循環器専門医、認定内科医
TOEIC 855点
受賞歴
計 12演題（Young Investigators Award 9演題）
12.
令和5年度 知財功労賞 経済産業大臣表彰受賞
11.
経済産業省主催ジャパンヘルスケビジネスコンテスト2018 最優秀賞
10.
American Heart Association Annual Scientific Sessions 2015 Cardiovascular
Disease in the Young Early Career Investigator Award Finalist （honorable
mention）（2015年11月8日）
9.
International Heart Journal Ueda Award 最優秀論文賞（2015年9月1日）
8.
American Heart Association Quality of Care and Outcomes Research Scientific
Sessions 2015 Young Investigator Award Finalist （honorable mention）（2015年4月29日）
7.
American College of Cardiology Annual Scientific Sessions 2014 Cardiovascular
Health Outcomes and Population Genetics Young Investigators Award Finalist（honorable
mention）（2014年3月31日）。
6.
American Heart Association Annual Scientific Sessions 2013 Elizabeth Barrett-Connor
Research Award for Young Investigators in Training Finalist（honorable mention）（2013年11月17日）
5.
第61回日本心臓病学会総会 Young Investigators Award 最優秀演題賞（2013年9月20日）
4.
第33回心筋梗塞研究会 Young Investigators Award 最優秀演題賞（2013年7月6日）
3.
第49回日本循環器予防学会総会 Young Investigators Award 最優秀演題賞（2013年6月14日）
2.
第16回日本心不全学会総会 Young Investigators Award 優秀演題賞(2012年12月2日）
1.
第111回日本循環器学会近畿地方会 Young Investigators Award 優秀演題賞（2011年6月25日）
英字論文
計 92編（筆頭著者 24編、2nd or Corresponding or Last 38編）
92.
Shinmoto K, Torikai Y, Hara M. Impact of somato-cognitive coordination therapy on activities of daily living in a patient with Huntington's disease. BMJ Case Rep 2024 in press.
91.
Hara M, Tamaki M. Development and functional characterization of a novel respiratory
mask with full accordion cushioning to prevent air leaks and pressure injuries
during non-invasive ventilation. Crit Care 2024;28:353.
90.
Yokoi K, Tanaka A, Yoshioka G, Hara M, Kamohara K, Node K. Accuracy of outcome ascertainment in long-term mortality
after coronary artery bypass grafting. Mayo Clin Proc Inn Qual Out. 2024;8:502-504.
89.
Kitano M, Nakamoto M, Kawanishi K, Hara M, Kudo S. Analyzing muscle thickness changes in lateral abdominal muscles while exercising using virtual reality. J Phys Ther Sci. 2024;36:372–7.
88.
Hara M, Murakawa Y, Wagatsuma T, Shinmoto K, Tamaki M. Feasibility of somato-cognitive
coordination therapy using virtual reality for patients with advanced severe
Parkinson’s disease. J Parkinsons Dis. 2024;14:895-898.
87.
Yamaguchi T, Miwa T, Tamura K, Inoue F, Umezawa N, Maetani T, Hara M, Kanemaru S. Temporal virtual reality-guided, dual-task, body trunk-balance training in a sitting position improved persistent postural-perceptual dizziness: proof of concept. J NeuroEngineering Rehab 2022;19:92.
86.
Kaminohara J, Hara M, Uehara K, Suruga M, Yunoki K, Takatori M. Intravenous landiolol for the
prevention of atrial fibrillation after aortic root, ascending aorta, and
aortic arch surgery: a propensity score-matched analysis. JTCVS Open 2022;11:49-58.
85.
Nakamoto M, Kakuda A, Miyashita T, Kitagawa T, Kitano M, Hara M, Kudo S. Seated virtual reality-guided exercise improved gait in a postoperative hallux valgus case. Int J Environ Res Public Health 2021;18:13267.
84.
Nabeta T, Hara M, Naruke T, Maemura K, Oki T, Yazaki M, Fujita T, Ikeda Y, Ishii S, Koitabashi T, Ako J. Clinical valuables related to resolution of complete or advanced atrioventricular block after steroid therapy in patients with cardiac sarcoidosis. Journal of Arrhythmia. 2021;37:1093–1100.
83.
Shimomura Y, Hara M, Hirabayashi S, Kondo T, Mizuno S, Uchida M, Mukae J, Kawakita T, Fukuda
T, Kanda Y, Ota S, Ozawa Y, Eto T, Maruyama Y, Tanaka M, Nakano N, Kimura
T, Ichinohe T, Atsuta Y, Yanada M. Comparison of fludarabine, a myeloablative
dose of busulfan, and melphalan vs conventional myeloablative conditioning
regimen in patients with relapse and refractory acute myeloid leukemia
in non-remission status. Bone Marrow Transplant 2021;56:2302-2304.
82.
Yashima F, Hara M, Inohara T, Jinzaki M, Shimizu H, Fukuda K, Tanaka M, Yamamoto M, Watanabe
Y, Naganuma T, Shirai S, Yamawaki M, Tada N, Yamanaka F, Mizutani K, Ueno
H, Tabata M, Takagi K, Hayashida K on behalf of the OCEAN-TAVI registry.
Statin therapy for patients with aortic stenosis who underwent transcatheter
aortic valve implantation: a report from a Japanese multicentre registry.
BMJ Open 2021;11:e044319.
81.
Shimomura Y, Hara M, Konuma T, Itonaga H, Doki N, Ozawa Y, Eto T, Uchida N, Aoki J, Kato J,
Onishi Y, Takahashi S, Fukushima K, Nakamae H, Kawakita T, Tanaka J, Fukuda
T, Atsuta Y, Ishikawa T, Ishiyama K. Allogeneic hematopoietic stem cell
transplantation for myelodysplastic syndrome in adolescent and young adult
patients. Bone Marrow Transplant 2021;56:2510-2517.
80.
Nogi K, Soeda T, Hara M, Iwama H, Toyokawa N, Sakai S, Yano H, Iwai A, Hashimoto Y, Fujimoto H,
Suzuki M, Nakai T, Doi N, Saito Y. Functional assessment of intermediate
coronary artery stenosis with 4-Fr catheters. Heart Vessels 2021;36:638–645.
79.
Shimomura Y, Hara M, Yamamoto H, Uchida N, Kawakita T, Ashida T, Takada S, Ikeda T, Morishige
S, Maruyama Y, Wake A, Ichinohe T, Fukuda T, Takanashi M, Atsuta Y, Ishikawa
T. Adding melphalan to fludarabine and a myeloablative dose of busulfan
improved survival after allogeneic hematopoietic stem cell transplantation
in a propensity score-matched cohort of hematological malignancies. Bone
Marrow Transplant 2021;56:1691-1699.
78.
Omori H, Hara M, Sobue Y, Kawase Y, Mizukami T, Tanigaki T, Hirata T, Ota H, Okubo M,
Hirakawa A, Suzuki T, Kondo T, Leipsic J, Norgaard BL, Matsuo H. Determination
of the optimal measurement point for fractional flow reserve derived from
CT angiography using pressure wire assessment as reference. Am J Roentgenol.
2021;216:1–8.
77.
Omachi N, Ishikawa H, Hara M, Nishihara T, Yamaguchi Y, Yamamoto Y, Yomoto M, Hattori T, Kitaguchi
K, Yamamoto S, Kawaguchi T, Fukuzawa M. The impact of bronchial artery
embolization on the quality of life of patients with haemoptysis: A prospective
observational study. Euro Radiol 2021;31:5351-5360.
76.
Pak M, Hara M, Miura S, Furuya M, Tamaki M, Okada T, Watanabe N, Endo A, Tanabe K. Delirium
is associated with high mortality in older adult patients with acute decompensated
heart failure. BMC Geriatr 2020;20:524.
75.
Okai T, Mizutani K, Hara M, Yamaguchi T, Ogawa M, Ito A, Iwata S, Izumiya Y, Takahashi Y, Shibata
T, Yoshiyama M. Presence of mitral stenosis is a risk factor of new development
of acute decompensated heart failure early after transcatheter aortic valve
implantation. Open Heart. 2020;7:e001348.
74.
Goto K, Hara M, Yamazaki Y, Urata T, Shimizu Y, Shimizu N. Smaller cross-sectional areas
of the hamstring tendon measured from preoperative ultrasonography are
likely to need additional gracilis harvesting for double-bundle anterior
cruciate ligament reconstructions. Knee Surg & Relat Res 2020;32:34.
73.
Kadoya Y, Hara M, Takahari K, Ishida Y, Tamaki M. Disease control status and safety of
telemedicine in patients with lifestyle diseases: a multicenter prospective
observational study in Japan. Circ Rep 2020;2:351-356.
72.
Omori H, Ota H, Hara M, Kawase Y, Tanigaki T, Hirata T, Sobue Y, Okubo M, Kamiya H, Matsuo H.
Effect of PCSK-9 inhibitors on lipid-rich vulnerable coronary plaque assessed
by near-infrared spectroscopy. JACC Cardiovasc Imaging 2020;13:1639-1641.
71.
Hara M, Hayashi K, Kitamura T, Honda M, Tamaki M. A nationwide randomised, double-blind,
placebo-controlled physicians’ trial of loxoprofen for the treatment of
fatigue, headache, and nausea after hangovers. Alcohol 2020;8:21-25.
70.
Shimomura Y, Hara M, Maruoka H, Yabushita T, Ishikawa T. Measurable residual disease evaluated
by flow cytometry using leukemia associated immune phenotypes following
allogeneic stem cell transplantation is associated with high relapse rates
in patients with acute myeloid leukemia. Leuk and Lymphoma 2020;61:745-748.
69.
Mizutani K, Hara M, Nakao K, Yamaguchi T, Okai T, Nomoto Y, Kajio K, Kaneno Y, Yamazaki T,
Ehara S, Kamimori K, Izumiya Y, Yoshiyama M. Association between debulking
area of rotational atherectomy and platform revolution speed - frequency
domain optical coherence tomography analysis. Catheter Cardiovasc Interv
2020;95:E1-E7.
68.
Ishikawa H, Omachi N, Ryuge M, Takafuji J, Hara M. Erratic coil migration in the bronchus after bronchial artery embolization.
Respirol Case Rep. 2019;7:e00478.
67.
Omon K, Hara M, Ishikawa H. Virtual reality-guided dual-task body trunk balance training
in a sitting position improved walking ability without improving leg strength.
Prog Rehabil Med 2019;4:20190011.
66.
Moriyama Y, Hara M, Aratani S, Ishikawa H, Kono K, Tamaki M. The association between six month intra-dialytic resistance training and muscle strength or physical performance in patients with maintenance hemodialysis: a multicenter retrospective observational study. BMC Nephrology 2019;20:172.
65.
Shimomura Y, Hara M, Tachibana T, Ohashi K, Sakura T, Fukuda T, Nakazawa H, Iwato K, Kanda
Y, Ikeda T, Eto T, Kanda J, Ichinohe T, Atsuta Y, Ishikawa T, Ishiyama
K. Outcomes of second allogeneic hematopoietic stem cell transplantation
in patients with relapse of myelodysplastic syndrome. Br J Haematol 2019;186:86-90.
64.
Kajio K, Mizutani K, Hara M, Nakao M, Okai T, Ito A, Takahashi Y, Iwata S, Shimono T, Izumiya Y, Murakami
T, Shibata T, Yoshiyama M. Self-expandable transcatheter aortic valve replacement
is associated with frequent periprocedural stroke detected by diffusion-weighted
magnetic resonance imaging. J Cardiol 2019;74:27-33.
63.
Omori H, Kawase Y, Hara M, Tanigaki T, Okamoto S, Hirata T, Kikuchi J, Ota H, Sobue Y, Miyake T,
Kawamura I, Okubo M, Kamiya H, Tsuchiya K, Suzuki T, Pijls N.H.J, Matsuo
H. Feasibility and safety of jailed-pressure wire technique using durable
optical fiber pressure wire for intervention of coronary bifurcation lesions.
Catheter Cardiovasc Interv 2019;94:E61-E66.
62.
Nagura F, Kataoka A, Hara M, Kozuma K, Watanabe Y, Nakashima M, Hioki H, Kawashima H, Nara Y, Shirai
S, Tada N, Araki M, Naganuma T, Yamanaka F, Ueno H, Tabata M, Mizutani
K, Higashimori A, Takagi K, Yamamoto M, Hayashida K; on behalf of the OCEAN-TAVI
investigators. Association between valvuloarterial impedance after transcatheter
aortic valve implantation and 2-year mortality in elderly patients with
severe symptomatic aortic stenosis: the OCEAN-TAVI Registry. Heart Vessels
2019;34:1031-1039.
61.
Butter C, Kaneko H, Tambor G, Hara M, Neuss M, Hoelschermann F. Clinical utility of intraprocedural three-dimensional
integrated image guided transcatheter aortic valve implantation using novel
automated computed tomography software: A single center preliminary experience.
Catheter Cardiovasc Interv 2019;93:722-728.
60.
Ryuge M, Hara M, Hiroe T, Omachi N, Minomo S, Kitaguchi K, Youmoto M, Asakura N, Sakata
Y, Ishikawa H. Mechanisms of recurrent hemoptysis after super-selective
bronchial artery coil embolization: a single center retrospective observational
study. Euro Radiol 2019;29:707-715.
59.
Ichiba T, Hara M, Miyahara K, Urashima M, Shintani A, Naitou H, Higashi R. Impact of computed
tomography evaluation before colonoscopy for the management of colonic
diverticular hemorrhage. J Clin Gastroenterol. 2019;53:e75-e83.
58.
Hara M, Kitamura T, Murakawa Y, Shimba K, Yamaguchi S, Tamaki M. Safety and feasibility
of dual-task rehabilitation program for body trunk balance using virtual
reality and three-dimensional tracking technologies. Prog Rehabil Med 2018;3:20180016.
57.
Mizutani K, Hara M, Nakao M, Okai T, Kajio K, Murakami T, Shibata T, Yoshiyama M, Naganuma T, Yamanaka F, Higashimori A, Tada N, Takagi K, Araki M, Ueno H, Tabata M, Shirai S, Watanabe Y, Yamamoto M, Hayashida K. Is elevation of N-terminal pro-B-type natriuretic peptide at discharge associated with 2-year composite endpoint of all-cause mortality and heart failure hospitalization after transcatheter aortic valve implantation? Insights from a multicenter prospective OCEAN-TAVI registry in Japan. BMJ Open 2018;8:e021468.
56.
Kagase A, Yamamoto M, Shimura T, Kano S, Tsuzuki M, Kodama A, Koyama Y, Shibata K, Hara M, Tada N, Naganuma T, Araki M, Yamanaka F, Shirai S, Watanabe Y, Hayashida K. Sex-specific grip strength after transcatheter aortic valve replacement in elderly patients. JACC Cardiovasc Interv. 2018;11:100-101.
55.
Shimomura Y, Hara M, Katoh D, Hashimoto H, Ishikawa T. Enlarged spleen is associated with
low neutrophil and platelet engraftment rates and poor survival after allogeneic
stem cell transplantation in patients with acute myeloid leukemia and myelodysplastic
syndrome. Ann Hematol. 2018;97:1049-1056.
54.
Nakashima K, Aoshima M, Nakashita T, Hara M, Otsuki A, Noma S, Misawa M, Otsuka Y, Motojima S. Low-dose trimethoprim-sulfamethoxazole
treatment for pneumocystis pneumonia in non-human immunodeficiency virus-infected
immunocompromised patients: a single-center retrospective observational
cohort study. J Microbiol Immunol Infect. 2018;51:810-820.
53.
Fujii T, Matsuyama T, Takeuchi J, Hara M, Kitamura T, Yamauchi-Takihara K. Women among first authors in Japanese
cardiovascular journals: an observational study. Int Heart J. 2018;59:372-377.
52.
Fujino A, Otsuji S, Hasegawa K, Arita T, Takiuchi S, Fujii K, Yabuki M,
Ibuki M, Nagayama S, Ishibuchi K, Kashiyama T, Ishii R, Tamaru Y, Yamamoto
W, Hara M, Higashino Y. Accuracy of J-CTO score derived from computed tomography
versus angiography to predict successful percutaneous coronary intervention.
JACC Cardiovasc Imaging 2018;11:209-217.
51.
Aratani S, Hara M, Nagahama M, Taki F, Futatsuyama M, Tsuruoka S, Komatsu Y. A low initial
serum sodium level is associated with an increased risk of overcorrection
in patients with chronic profound hyponatremia : a retrospective cohort
analysis. BMC Nephrology. 2017;18:316.
50.
Ichiba T, Hara M, Yunoki K, Urashima M, Naito H. Serial follow-up evaluation with computed
tomography after conservative medical treatment in patients with symptomatic
spontaneous isolated superior mesenteric artery dissection. Vasc Endovascular
Surg. 2017;51:538-544.
49.
Yokoi K, Hara M, Ueda Y, Yamamoto K, Ota K, Kabata D, Kitamura T, Sakata Y, Shintani A. Epidemiological and outcome data in patients with deep vein thrombosis with and without malignancy. Heart Vessels. 2017;32:1469-1477.
48.
Matsuyama T, Fujii T, Takeuchi J, Hara M, Kitamura T. Prevalence of randomized controlled trials in Japanese cardiovascular
journals: a descriptive study. Heart Asia. 2017; 9: e010929.
47.
Fujii T, Nakayama S, Hara M, Koizumi W, Itabashi T, Saito M. Comprehensive comparison of six cutout
risks demonstrated that tip apex distance was the most important predictive
index for cutout after internal fixation of intertrochanteric fracture
in women. JBJS Open Access. 2017:e0022.
46.
Ichiba T, Hara M, Nishikawa K, Tanabe T, Urashima M, Naitou H. Comprehensive evaluation of diagnostic and treatment strategies for idiopathic spinal subarachnoid hemorrhage. J Stroke Cerebrovasc Dis. 2017;26:2840-2848.
45.
Mizutani K, Hara M, Iwata S, Murakami T, Shibata T, Yoshiyama M, Naganuma T, Yamanaka F, Higashimori A, Tada N, Takagi K, Araki M, Ueno H, Tabata M, Shirai S, Watanabe Y, Yamamoto M, Hayashida K. Elevation of B-type natriuretic peptide at discharge is associated with 2-year mortality after transcatheter aortic valve replacement in patients with severe aortic stenosis: insights from a multicenter prospective OCEAN-TAVI (Optimized Transcatheter Valvular Intervention-Transcatheter Aortic Valve Implantation) registry. J Am Heart Assoc. 2017;6:e006112.
44.
Kaneko H, Hara M, Mizutani K, Yoshiyama M, Yokoi K, Kabata D, Shintani A, Kitamura T. Improving
outcomes of witnessed out-of-hospital cardiac arrest after implementation
of international liaison committee on resuscitation 2010 consensus: a nationwide
prospective observational population-based study. J Am Heart Assoc. 2017;6:e004959.
43.
Mizutani M, Takami A, Hara M, Mizuno S, Yanada M, Chou T, Uchiyama H, Ohashi K, Miyamoto T, Ozawa Y,
Imataki O, Kobayashi N, Uchida N, Kanamori H, Kamimura T, Eto T, Onizuka
M, Tanaka J, Atsuta Y, Yano S. Comparison of autologous and unrelated transplants
for cytogenetically normal acute myeloid leukemia. Biol Blood Marrow Transplant.
2017;23:1447-1454.
42.
Shimomura Y, Hara M, Hashimoto H, Ishikawa T. Elevated bone marrow eosinophil count is associated
with high incidence of severe acute graft versus host disease after allogeneic
hematopoietic stem cell transplantation. Bone Marrow Transplant 2017;52:1311-1316.
41.
Yokoi K, Hara M, Ueda Y, Sumitsuji S, Awata M, Salah YK, Kabata D, Shintani A, Sakata Y. Ideal guiding catheter position during bilaterally engaged percutaneous coronary intervention. Am J Cardiol. 2017;119:1518-1524.
40.
Ishikawa H, Hara M, Ryuge M, Takafuji J, Youmoto M, Akira M, Nagasaka Y, Kabata D, Yamamoto K, Shintani A. Efficacy and safety of super-selective bronchial artery coil embolization for hemoptysis: a single center retrospective observational study. BMJ Open 2017;7:e014805.
39.
Mizutani K, Hara M, Ishikawa H, Nishimura S, Ito A, Iwata S, Takahashi Y, Sugioka K, Murakami
T, Shibata T, Yoshiyama M. Safety and efficacy of simultaneous biplane
mode of 3-dimensional transesophageal echocardiography-guided antegrade
multiple-inflation balloon aortic valvuloplasty in patients with severe
aortic stenosis. Circ J. 2017;81:748-754.
38.
Hara M, Hayashi K, Kitamura T. Outcomes differ by first documented rhythm after witnessed out-of-hospital cardiac arrest in children; an observational study with prospective nationwide population-based cohort database in Japan. Eur Heart J Qual Care Clin Outcomes 2017;3:83-92.
37.
Ichiba T, Hara M, Yunoki K, Urashima M, Harano M, Naitou H, Yamamoto K, Shintani A. Baseline
disease is more important predictor of intestinal necrosis than CT findings
in patients with acute mesenteric ischemia. Am J Emerg Med 2016;34:2261-2265.
36.
Hara M, Sakata Y, Nakatani D, Suna S, Nishino M, Sato H, Kitamura T, Nanto S,
Hori M, Komuro I, on behalf of the OACIS Investigators. Impact of coronary
collaterals on in-hospital and 5-year mortality after ST-elevation myocardial
infarction in the contemporary percutaneous coronary intervention era:
a prospective observational study. BMJ Open. 2016;6:e011105.
35.
Ichiba T, Hara M, Yunoki K, Urashima M, Naitou H. Impact of noninvasive conservative medical
treatment for symptomatic isolated celiac artery dissection. Circ J. 2016;80:1445-1451.
34.
Kinoshita T, Yoshiya K, Fujimoto Y, Kajikawa R, Kiguchi T, Hara M, Wakayama A, Yoshimine T. Decompressive craniectomy in conjunction with
evacuation of intracranial hemorrhagic lesions is associated with worse
outcomes in elderly patients with traumatic brain injury: a propensity
score analysis. World Neurosurg. 2016;89:187-192.
33.
Mizutani M, Hara M, Fujita H, Aoki J, Kanamori H, Ohashi K, Usuki K, Fukuda T, Chou T, Tanaka
J, Atsuta Y, Takami A. Comparable outcomes between autologous and allogeneic
transplant for adult Q2 acute myeloid leukemia in first CR. Bone Marrow
Transplant. 2016;51:645-653.
32.
Kagiyama N, Toki M, Hara M, Fukuda S, Aritaka S, Miki T, Ohara M, Hayashida A, Hirohata A, Yamamoto
K, Yoshida K. Efficacy and accuracy of novel automated mitral valve quantification:
Three-dimensional transesophageal echocardiographic study. Echocardiography.
2016;33:756-763.
31.
Nishino M, Okamoto N, Tanaka A, Mori N, Hara M, Yano M, Makino N, Egami Y, Shutta R, Tanouchi J. Different risk factors for bleeding and discontinuation between dabigatran and rivaroxaban. J Cardiol. 2016;68:156-160.
30.
Hara M, Sakata Y, Nakatani D, Suna S, Nishino M, Sato H, Kitamura T, Nanto S,
Hamasaki T, Hori M, Komuro I, on behalf of the OACIS Investigators. Subclinical
elevation of high-sensitive troponin T levels at the convalescent stage
is associated with increased 5-year mortality after ST-elevation myocardial
infarction. J Cardiol. 2016;67:314-320.
29.
Hara M, Hayashi K, Hikoso S, Sakata Y, Kitamura T. Different impacts of time
from collapse to first cardiopulmonary resuscitation on outcomes after
witnessed out-of-hospital cardiac arrest in adults. Circ Cardiovasc Qual
Outcomes. 2015;8:277-284.
28.
Nakamura D, Lee Y, Yoshimura T, Taniike M, Makino N, Kato H, Egami Y, Shutta
R, Tanouchi J, Yamada Y, Hara M, Sakata Y, Hamasaki T, Nishino M. Different serial changes in the neointimal
condition of sirolimus-eluting stents and paclitaxel-eluting stents:an
optical coherence tomographic study. Eurointervention. EuroIntervention.
2014;10:924-933.
27.
Hara M. Re: Angiotensin receptor blocker in patients with ST segment elevation
myocardial infarction with preserved left ventricular systolic function:
prospective cohort study. BMJ 2014;349:g6650. (Link)
26.
Hara M, Sakata Y, Nakatani D, Suna S, Usami M, Matsumoto S, Ozaki K, Nishino
M, Sato H, Kitamura T, Nanto S, Hamasaki T, Tanaka T, Hori M, Komuro I,
on behalf of the OACIS Investigators. Reduced risk of recurrent myocardial
infarction in homozygous carriers of the chromosome 9p21 rs1333049 C risk
allele in the contemporary percutaneous coronary intervention era: a prospective
observational study. BMJ Open 2014;4:e005438.
25.
Hara M, Sakata Y, Nakatani D, Suna S, Usami M, Matsumoto S, Sugitani T, Nishino
M, Sato H, Kitamura T, Nanto S, Hamasaki T, Hori M, Komuro I, on behalf
of the OACIS Investigators. Comparison of 5-year survival after acute myocardial
infarction using angiotensin converting enzyme inhibitor versus angiotensin
II receptor blocker. Am J Cardiol. 2014;114:1-8.
24.
Edahiro R, Sakata Y, Nakatani D, Suna S, Usami M, Matsumoto S, Hara M, Kitamura T, Sato H, Yamashita S, Nanto S, Hikoso S, Sakata Y, Hori M, Hamasaki T, Komuro I, on behalf of the OACIS Investigators. Association of lifestyle-related factors with circadian onset patterns of acute myocardial infarction: a prospective observational study in Japan. BMJ Open. 2014;4:e005067.
23.
Hara M, Sakata Y, Nakatani D, Suna S, Usami M, Matsumoto S, Sugitani T, Ozaki
K, Nishino M, Sato H, Kitamura T, Nanto S, Hamasaki T, Tanaka T, Hori M,
Komuro I, on behalf of the OACIS Investigators. Renin-angiotensin-aldosterone
system polymorphisms and five-year mortality in survivors of acute myocardial
infarction: a report from the Osaka Acute Coronary Insufficiency Study.
Int Heart J. 2014;55:190-196.
22.
Usami M, Sakata Y, Nakatani D, Suna S, Matsumoto S, Hara M, Kitamura T, Ueda Y, Iwakura K, Sato H, Hamasaki T, Nanto S, Hori M, Komuro
I. Clinical impact of acute hyperglycemia on development of diabetes mellitus
in non-diabetic patients with acute myocardial infarction. J Cardiol. 2014;63:274-280.
21.
Kitamura T, Sakata Y, Nakatani D, Suna S, Usami M, Matsumoto S, Hara M, Hamasaki T, Nanto S, Sato H, Hori M, Iso H, Komuro I. Living alone and risk of cardiovascular events following discharge after acute myocardial infarction in Japan. J Cardiol. 2013;62:257-262.
20.
Matsumoto S, Sakata Y, Nakatani D, Suna S, Usami M, Hara M, Kitamura T, Hamasaki T, Nanto S, Kawahara Y, Komuro I. Circulating p53-responsive
microRNAs are predictive indicators of heart failure after acute myocardial
infarction. Circ Res. 2013;113:322-326.
19.
Hara M, Sakata Y. Polyunsaturated fatty acids in heart failure. Circ J. 2013;77:1917-1918.
18.
Hara M, Sakata Y, Nakatani D, Suna S, Usami M, Matsumoto S, Hamasaki T, Doi Y, Nishino M, Sato H, Kitamura T, Nanto S, Hori M, Komuro I; for the Osaka Acute Coronary Insufficiency Study (OACIS) Investigators. Low levels of serum n-3 polyunsaturated fatty acids are associated with worse heart failure-free survival in patients after acute myocardial infarction. Circ J. 2013;77:153-162.
17.
Suna S, Sakata Y, Nakatani D, Okuda K, Shimizu M, Usami M, Matsumoto S, Hara M, Ozaki K, Mizuno H, Minamino T, Takashima S, Nishino M, Matsumura Y, Takeda
H, Tanaka T, Sato H, Hori M, Komuro I. Decreased mortality associated with
statin treatment in patients with acute myocardial infarction and lymphotoxin-alpha
C804A polymorphism. Atherosclerosis. 2013;227:373-379.
16.
Matsumoto S, Nakatani D, Sakata Y, Suna S, Shimizu M, Usami M, Hara M, Sumitsuji S, Nanto S, Sasaki T, Hamasaki T, Sato H, Hori M, Komuro I;
Osaka Acute Coronary Insufficiency Study (OACIS) Group. Elevated serum
heart-type Fatty Acid-binding protein in the convalescent stage predicts
long-term outcome in patients surviving acute myocardial infarction. Circ
J. 2013;77:1026-1032.
15.
Nakatani D, Sakata Y, Suna S, Usami M, Matsumoto S, Shimizu M, Hara M, Uematsu M, Fukunami M, Hamasaki T, Sato H, Hori M, Komuro I; Osaka Acute Coronary Insufficiency Study (OACIS) Investigators. Impact of beta blockade therapy on long-term mortality after ST-segment elevation acute myocardial infarction in the percutaneous coronary intervention era. Am J Cardiol. 2013;111:457-464.
14.
Sakata Y, Nakatani D, Shimizu M, Suna S, Usami M, Matsumoto S, Hara M, Sumitsuji S, Kawano S, Iwakura K, Hamasaki T, Sato H, Nanto S, Hori M,
Komuro I. Oral treatment with nicorandil at discharge is associated with
reduced mortality after acute myocardial infarction. J Cardiol. 2012;59:14-21.
13.
Muratsu J, Hara M, Mizote I, Asano Y, Sakata Y, Saito S, Matsumiya G, Sawa Y, Komuro I.
The impact of cardiac resynchronyzation therapy in an end-stage heart failure
patient with a left ventricular assist device as a bridge to recovary.
A case report. Int Heart J. 2011;52:246-247.
12.
Katsuragi S, Hara M, Mizote I, Sakata Y, Yamauchi-Takihara K, Komuro I. Adjunctive tadalafil
therapy for managing pulmonary hypertension in a patient with obesity hypoventilation
syndrome. J Cardiol Cases 2011;4:e126-128.
11.
Hara M, Mizuno H, Mizote I, Nakatani D, Asano Y, Sakata Y, Nanto S, Komuro I.
Clinical impact of off-label cardiac resynchronization therapy in end-stage
heart failure patients on continuous intravenous inotrope. Clin Cardiol.
2011;34:714-720.
10.
Hara M, Nishino M, Taniike M, Makino N, Kato H, Egami Y, Shutta R, Tanouchi J,
Hunatsu T, Taniguchi K, Yamada Y. Impact of 64 multi-detector computed
tomography for the evaluation of aortic paraprosthetic regurgitation. J
Cardiol. 2011;58:294-299.
9.
Hara M, Nishino M, Taniike M, Makino N, Kato H, Egami Y, Shutta R, Tanouchi J,
Yamada Y. Serial angioscopic evaluation of neointimal coverage and incidence
of thrombus formation after Paclitaxel-eluting stent implantation; comarison
between 6- and 18-month follow-up. Clin Cardiol. 2011;34:322-326.
8.
Hara M, Mizote I, Nakaoka Y, Tanaka H, Asano Y, Sakata Y, Komuro I. A case of
non-cardiogenic acute pulmonary edema in a patient with POEMS syndrome-associated
pulmonary arterial hypertension. Ann Hematol. 2011;90:489-490.
7.
Hara M, Nishino M, Taniike M, Makino N, Kato H, Egami Y, Shutta R, Yamaguchi H, Tanouchi J, Yamada Y. Chronic effect of right ventricular pacing on left ventricular rotational synchrony in patients with complete atrioventricular block. Echocardiography. 2011;28:69-75.
6.
Shimomura Y, Hara M, Mizote I, Nakaoka Y, Tanaka H, Asano Y, Sakata Y, Komuro I. Sildenafil
and steroid therapy effectively improved POEMS syndrome-associated pulmonary
arterial hypertension. Int J Hematol. 2010;92:774-776.
5.
Hara M, Nishino M, Taniike M, Makino N, Kato H, Egami Y, Shutta R, Yamaguchi H, Tanouchi J, Yamada Y. High incidence of thrombus formation at 18 months after paclitaxel-eluting stent implantation: angioscopic comparison with sirolimus-eluting stent. Am Heart J. 2010;159:905-910.
4.
Hara M, Nishino M, Yamada Y. Cardiac tumor-like mass in a patient with systemic
vasculitis. J Am Coll Cardiol. 2010;55:1882.
3.
Hara M, Nishino M, Taniike M, Makino N, Kato H, Egami Y, Shutta R, Yamaguchi
H, Tanouchi J, Yamada Y. Difference of neointimal formational pattern and
incidence of thrombus formation among 3 kinds of stents: an angioscopic
study. JACC Cardiovasc Interv. 2010;3:215-220.
2.
Hara M, Nishino M. Impact of intravascular ultrasound for the treatment of calcified
infrarenal aortic stenosis: a case report study. Catheter Cardiovasc Interv.
2008;72:867-870.
1.
Hara M, Nishino M, Matsuoka K, Yamada Y. Heavily calcified chronic total occlusion of common iliac artery successfully treated with Tornus microcatheter and rotational atherectomy. J Vasc Surg. 2008;48:758-760.
和文論文
計 20編
20. （査読あり）
我妻朋美, 村川雄一朗, 影近卓大, 新本啓人, 原正彦. 学校生活に困難さを抱える小児発達性協調運動障害に対する仮想現実技術を用いた体性認知協調療法の検討. 神経治療学 2024 in press
19.
村川雄一朗,新本啓人, 原正彦. 仮想現実技術を用いた体性認知協調療法による整形・災害外科疾患治療への新たなアプローチ. 整・災害 2024;67:1483-1487.
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原正彦. 仮想現実技術を用いた難治性慢性腰痛の新たな治療戦略. 治療 2024;106:574-577.
17.（査読あり）
村川雄一朗, 仲上恭子, 新本啓人, 原正彦. 仮想現実技術を用いた脳再プログラミング療法が脳性麻痺患者の痙縮に及ぼす効果. 神経治療学 2024;41:55-59.
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原正彦. 仮想現実（Virtual Reality）技術を用いた離床練習. Early Mobilization Journal 2024;10:1-5.
15.
原正彦. 仮想現実（VR）技術を用いた最新リハビリテーション医療. Precision Medicine 2023;6:1031-1034.
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原正彦. 仮想現実（VR）技術を用いた新しい転倒予防. 治療 2023;105:1270-1275.
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原正彦, 村川雄一朗, 新本啓人. Virtual Reality技術を用いた回復期リハビリテーション医療の未来. 臨床リハ 2022;31(13):1226-1232.
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村川雄一朗, 東福隆太郎, 國師美里, 原正彦. VR 技術を活用した在宅リハビリテーション医療の展望. 建築保全センター「Re」 2022;10(216):30-33.
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北野雅之, 原正彦. 仮想現実（VR）技術がもたらす新時代のリハビリテーション革命. NOMURA Healthcare note 2022;22(5):1-11.
10.
村川雄一朗, 原正彦. VR技術を用いたリハビリテーション医療の工学的理論背景．リハビリテーションエンジニアリング 2022;37(3):122-126.
9.
原正彦. リハビリテーション医学における仮想現実（VR）技術を用いたトレーニング. 総合リハ 2022;50(4):351-358.
8.（査読あり）
原正彦. ゲームがつくる患者の未来 -リハビリにおけるVRゲーム技術の応用. 日本臨床麻酔学会誌 2022;42(1):106-110.
7.
原正彦. VR技術のリハビリテーション医療への応用. 臨床リハ 2021;30(8): 877-880.
6.
原正彦. 臨床研究の進め方について. リハビリテーション栄養 2021;5(1):71-73.
5.
原正彦. VRを活用したリハビリテーション. medicina 2021;58(6):864-867.
4.
原正彦. VRリハビリ機器開発を通した医工連携による事業化の考え方と実際. BIO INDUSTRY 2020;37(6):39-46.
3.（査読あり）
原正彦. 仮想現実（VR）技術を用いたリハビリテーションは慢性疼痛患者の福音となるか？ 運動器疼痛学会誌 2020;12(2):90-93.
2.
原正彦. Virtual realityを利用した理学療法. 理学療法ジャーナル 2020;54(1):90.
1.（査読あり）
原正彦, 宮本哲也, 黒田祐一, 小澤修一. 救急救命士による薬剤投与が社会復帰に貢献した心肺停止の1例. 心臓 2007;39(1):39-43.